Editorial: Hope, Hypothesis, and the Inhibin Receptor. Does Specific Inhibin Binding Suggest There Is a Specific Inhibin Receptor?
نویسندگان
چکیده
منابع مشابه
Is the action of inhibin mediated via a unique receptor?
The receptor system and the molecular mechanisms by which inhibin acts on its target cells are poorly understood, in contrast to the situation for the structurally related molecule, activin. On the basis of evidence that the biological action of inhibin in a number of systems resembles that of an activin antagonist, it has been contended that inhibin operates by competition for the activin rece...
متن کاملSecretion of inhibin A and inhibin B throughout pregnancy and the early postpartum period in chimpanzees.
Plasma concentrations of inhibin A and inhibin B during pregnancy and early lactation in chimpanzees were determined by enzyme-linked immunosorbent assay (ELISA). Plasma samples were taken from five pregnant chimpanzees at 6-9, 10, 20 and 25 weeks of pregnancy, and following parturition. Throughout pregnancy and the early postpartum period, circulating inhibin A and inhibin B concentrations rem...
متن کاملInhibin A, inhibin B and activin A in the follicular fluid of regularly cycling women.
Recent measurements of circulating inhibin A and inhibin B concentrations indicate that inhibin B may play an important role in the selection of dominant follicles. The concentrations of inhibin A, inhibin B and activin A were measured in the follicular fluids of 61 individual follicles (4.8-20 mm in diameter) from 47 regularly cycling women using specific two-site enzyme-linked immunosorbent a...
متن کاملCLINICAL STUDY Inhibin a-subunit and the inhibin coreceptor betaglycan are downregulated in endometrial carcinoma
Objective: In the present study we evaluated the protein distribution and mRNA levels of inhibin a-subunit and its coreceptor betaglycan in endometrial adenocarcinoma. Design: Two groups of postmenopausal women were studied: the first group had recently diagnosed endometrial adenocarcinoma (n 1⁄4 16; age range 61–79 years), and the second group (n 1⁄4 12; age range 64 –78 years) had undergone h...
متن کاملSerum Inhibin A and Inhibin B Levels in Epithelial Ovarian Cancer Patients
THE AIM of our study was to examine serum inhibin A and inhibin B concentrations in ovarian cancer patients in relation to clinicopathological features and 5-year survival. MATERIAL AND METHODS We enrolled 90 epithelial ovarian cancer patients in our study, aged 45-81 years, who underwent optimal cytoreductive surgery. In all patients, serum inhibin A and inhibin B concentrations were measure...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 1999
ISSN: 0013-7227,1945-7170
DOI: 10.1210/endo.140.1.6547